Recent advance in nanotechnoloy and nanomaterials can make a very small gas chromatography possible using Carbon Nanotubes. Michael Strano's group in Massachusetts Institute of Technology has been developing a sensitive and nano-sized gas chromatography instrument based on carbon nanotubes. The main goal for this device was to make it so sensitive that it can detect analytes in the part-per-million range. To achieve the goal, single-walled carbon nanotubes were aligned between the electrodes. And a chromatography column was etched on a chip using a 100-micrometer trench. As a desired molecule binds to carbon nanotubes, the change in electrical signals are analyzed. You can use mean basicity to target whether desired molecules will bind very strongly.
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